Gene Therapy: A New Era

introduction
Promise, Danger and Progress
by Jesse Emspak

Section 1: What is Gene Therapy?

1.1 The Gen Fix
by Esther Landhuis

1.2 Gene therapy is coming of age
by Lauren Gravitz

Section 2: The Promise

2.1 Four success stories in gene therapy
by Jim Daley

2.2 Fix muscle wasting
by Dina Feine Maron

2.3 From the silence
by Dina Feine Maron

2.4 How gene therapy can reverse a form of congenital blindness
by Jean Bennett and Katherine A. High

2.5 Messenger RNA therapies finally arrived
by Drew Weissman

Section 3: The Challenges

3.1 Overcoming the long shadow of gene therapy
by Tanya Lewis

3.2 The challenge of finding genome-based cancer treatments
by Jonathan R Goodman

3.3 What gene therapy needs now: A good switch
by Jim Kozubek

Section 4: The Human Factor: History, Ethics and Assumptions

4.1 High hopes: balance between promises and reality
by Marla Broadfoot

4.2 We need more diversity in genomic databases
by Jonas Korlach

4.3 The human genome and the emergence of a skeptical biologist
by C Brandon Ogbunu

4.4 The inflated promise of genome medicine
by Eric Parens

4.5 All of us
by Stephanie Devaney