Study reviews over 72,000 Norwegian births over eight years – ZooHouseNews

Study reviews over 72,000 Norwegian births over eight years – ZooHouseNews

  • Science
  • November 23, 2022
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Conceiving within three months of a miscarriage or termination of pregnancy is not associated with an increased risk of adverse pregnancy outcomes, according to a new study published Nov. 22 in the open-access journal PLOS Medicine. The study suggests that contrary to current recommendations, women could attempt pregnancy after a previous miscarriage or induced termination without increased perinatal risks, and gives reassurance to those who wish to repeat it sooner than the guidelines recommend.

The World Health Organization recommends waiting six months after a miscarriage or abortion before trying to get pregnant again to avoid complications in the next pregnancy, but evidence to support this is scarce. Gizachew Tessema of the Curtin School of Population Health, Australia, and colleagues conducted a cohort study covering a total of 49,058 miscarriage births and 23,707 abortion births in Norway between 2008 and 2016. They examined six adverse outcomes: preterm birth, spontaneous preterm birth, small for gestational age, large for gestational age, preeclampsia, and gestational diabetes.

Compared to waiting 6 to 11 months after a miscarriage, there was a reduced risk of preterm gestation in babies conceived in less than six months and a reduced risk of gestational diabetes in women conceived in less than three months. After termination of pregnancy there was a slightly but not significantly increased risk of low gestational age for conception in less than three months compared to 6-11 months, but the risk of high for gestational age was higher in the group with an interpregnancy interval of 3- 5 months.

There was no evidence of a higher risk of adverse pregnancy outcomes in women with an IPI longer than 12 months after miscarriage or termination, except for a slightly increased risk of gestational diabetes. The authors acknowledge that the study was limited in that it lacked information on potential confounders, including pregnancy intent and health-focused behaviors. In addition, the data included only miscarriages recorded by the healthcare system.

The findings do not support current guidelines to wait six months after miscarriage or abortion and suggest the need to review these guidelines and provide up-to-date, evidence-based recommendations for women.

The authors add, “Based on this and other studies, we called for a review of existing World Health Organization recommendations for spacing after miscarriage.”

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Materials provided by PLOS. Note: Content can be edited for style and length.

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